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两性霉素B(1% DMSO)

  • 320.00元/件
  • 起订量:1 件
  • 供货总量:100 件
  • 发布时间:2021-04-21产品供应时间:长期有效

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  • 苏州博特龙免疫技术有限公司
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  • 经营范围:抗体制备,免疫佐剂,转染试剂和冠状病毒产品等
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  • 品牌:博奥龙
  • 所属分类:科研试剂 » 其它
  • 货号:BDXB0086-10
  • 规格:10ml
  • 分类:细胞培养与细胞活力
  • 计量单位:件
  • 最小起订量:1件
  • 供货总量:100件
  • 发货期限:自买家付款之日起4天内发货

    Amphotericin B is a polyene antifungal agent, first isolated by Gold et al from Streptomyces nodosus in 1955. It is an amphoteric compound composed of a hydrophilic polyhydroxyl chain along one side and a lipophilic polyene hydrocarbon chain on the other. Amphotericin B has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. After binding to sterols, it forms channels in the membranes, causing small molecules to leak out. Amphotericin B induces K+ leakage which is separate from its lethal actionn, as was demonstrated in humna erythrocytes and is due to the inhibitory effect on the Na+/K+ pump. At sub-lethal concentrations, this agent stimulates ehther the activity of some membrane enzymes or cellular metabolism, in particular stimulation of some cells of the immune system. Amphotericin B is poorly soluble in water and now available in four formulations. The classic amphotericin B deoxycholate formulation has been available since 1960 and is a colloidal suspension of amphotericin B. A bile salt, deoxycholate, is often used as the solubilizing agent.

关键词:两性霉素B(1% DMSO),供应,科研试剂,其它
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