公司介绍
武汉合研生物医药科技有限公司坐落于光谷生物城,是一家专注于提供新药发现阶段的技术服务,以中小微新药研发企业为服务主体的创新型公司。合研生物拥有一支训练有素的药物研发技术团队,提供的服务覆盖虚拟筛选、酶学靶点筛选、抗肿瘤药物活性评价、细胞功能学检测、药理病理学服务等各项技术,同时也提供可购买的商业化合物库。我们的技术团队在分子生物学、细胞生物学、结构生物学等领域具有丰富的经验,通过酶水平、细胞水平测定等技术平台帮助客户进行化合物筛选及化合物特性、作用机制等研究。合研生物以高效、高性价比的专业服务帮助客户更快地达到目标,帮助客户推进药物发现的进程。
我们的优势
Kinase激酶
酶学研究一直是药物研发的重要组成部分。合研生物拥有丰富的酶学筛选经验,酶学实验涵盖300多种筛选模型,包括了常见的组蛋白去乙酰酶类,组蛋白去甲基化酶,酪氨酸激酶,丝氨酸激酶,甲基化转移酶,磷酸二酯酶,DNA修复酶,热休克蛋白,免疫相关蛋白等。根据样本量的大小提供灵活的项目实施安排计划,可提供96孔和384孔两种板型的筛选模式,加速您的药物研发进程。
Kinase激酶
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|
|
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E148
|
ABL1
|
ADP-Glo
|
96/384 well
|
E149
|
ABL1(E255K)
|
ADP-Glo
|
96/384 well
|
E150
|
ABL1(T315I)
|
ADP-Glo
|
96/384 well
|
E151
|
ABL1(Y253F)
|
ADP-Glo
|
96/384 well
|
E152
|
ACK
|
ADP-Glo
|
96/384 well
|
E153
|
AKT1
|
ADP-Glo
|
96/384 well
|
E154
|
AKT2
|
ADP-Glo
|
96/384 well
|
E155
|
AKT3
|
ADP-Glo
|
96/384 well
|
E156
|
ALK2
|
ADP-Glo
|
96/384 well
|
E157
|
ALK4
|
ADP-Glo
|
96/384 well
|
E158
|
ALK6
|
ADP-Glo
|
96/384 well
|
E159
|
AMAPK(A1/B1/G2)
|
ADP-Glo
|
96/384 well
|
E160
|
AMPK(A1/B1/G1)
|
ADP-Glo
|
96/384 well
|
E161
|
AMPK(A2/B1/G1)
|
ADP-Glo
|
96/384 well
|
E162
|
ASK1
|
ADP-Glo
|
96/384 well
|
E163
|
Aurora A
|
ADP-Glo
|
96/384 well
|
E164
|
Aurora B
|
ADP-Glo
|
96/384 well
|
E165
|
AXL
|
ADP-Glo
|
96/384 well
|
E166
|
BRK
|
ADP-Glo
|
96/384 well
|
E167
|
BXM
|
ADP-Glo
|
96/384 well
|
E168
|
CAMK1γ
|
ADP-Glo
|
96/384 well
|
E169
|
CAMK2α
|
ADP-Glo
|
96/384 well
|
E170
|
CAMK2γ
|
ADP-Glo
|
96/384 well
|
E171
|
CAMKK1
|
ADP-Glo
|
96/384 well
|
E172
|
CDC7/DBF4
|
ADP-Glo
|
96/384 well
|
E173
|
CDK2/CyclinA2
|
ADP-Glo
|
96/384 well
|
E174
|
CDK2/CyclinE1
|
ADP-Glo
|
96/384 well
|
E175
|
CDK3/cyclinE1
|
ADP-Glo
|
96/384 well
|
E176
|
CDK5/p25
|
ADP-Glo
|
96/384 well
|
E177
|
CDK5/p35
|
ADP-Glo
|
96/384 well
|
E178
|
CDK6/CyclinD3
|
ADP-Glo
|
96/384 well
|
E179
|
CDK9/Cyclink
|
ADP-Glo
|
96/384 well
|
E180
|
CHK1
|
ADP-Glo
|
96/384 well
|
E181
|
CHK2
|
ADP-Glo
|
96/384 well
|
E182
|
CK1a1
|
ADP-Glo
|
96/384 well
|
E183
|
CK1γ1
|
ADP-Glo
|
96/384 well
|
E184
|
CK1ε
|
ADP-Glo
|
96/384 well
|
E185
|
CK2α1
|
ADP-Glo
|
96/384 well
|
E186
|
c-KIT
|
ADP-Glo
|
96/384 well
|
E187
|
CLK1
|
ADP-Glo
|
96/384 well
|
E188
|
CLK3
|
ADP-Glo
|
96/384 well
|
E189
|
c-MER
|
ADP-Glo
|
96/384 well
|
E190
|
CSK
|
ADP-Glo
|
96/384 well
|
E191
|
DAPK1
|
ADP-Glo
|
96/384 well
|
E192
|
DDR2
|
ADP-Glo
|
96/384 well
|
E193
|
DNA-PK
|
ADP-Glo
|
96/384 well
|
E194
|
DYRK2
|
ADP-Glo
|
96/384 well
|
E195
|
EGFR
|
ADP-Glo
|
96/384 well
|
E196
|
EGFR(L858R)
|
ADP-Glo
|
96/384 well
|
E197
|
EGFR(L861Q)
|
ADP-Glo
|
96/384 well
|
E198
|
EGFR(T790,L858R)
|
ADP-Glo
|
96/384 well
|
E199
|
EGFR(T790M)
|
ADP-Glo
|
96/384 well
|
E200
|
EIF2AK2
|
ADP-Glo
|
96/384 well
|
E201
|
EPHA1
|
ADP-Glo
|
96/384 well
|
E202
|
ERK1
|
ADP-Glo
|
96/384 well
|
E203
|
ERK2
|
ADP-Glo
|
96/384 well
|
E204
|
FAK
|
ADP-Glo
|
96/384 well
|
E205
|
FES
|
ADP-Glo
|
96/384 well
|
E206
|
FGFR1
|
ADP-Glo
|
96/384 well
|
E207
|
FGFR2
|
ADP-Glo
|
96/384 well
|
E208
|
FGFR3(K650E)
|
ADP-Glo
|
96/384 well
|
E209
|
FGFR4
|
ADP-Glo
|
96/384 well
|
E210
|
FLT1
|
ADP-Glo
|
96/384 well
|
E211
|
FLT3
|
ADP-Glo
|
96/384 well
|
E212
|
FLT3(D835Y)
|
ADP-Glo
|
96/384 well
|
E213
|
FMS
|
ADP-Glo
|
96/384 well
|
E214
|
FYN A
|
ADP-Glo
|
96/384 well
|
E215
|
GRK5
|
ADP-Glo
|
96/384 well
|
E216
|
GSK3α
|
ADP-Glo
|
96/384 well
|
E217
|
GSK3β
|
ADP-Glo
|
96/384 well
|
E218
|
HER2
|
ADP-Glo
|
96/384 well
|
E219
|
HER4
|
ADP-Glo
|
96/384 well
|
E220
|
HIPK1
|
ADP-Glo
|
96/384 well
|
E221
|
HPK1
|
ADP-Glo
|
96/384 well
|
E222
|
IGF1R
|
ADP-Glo
|
96/384 well
|
E223
|
IKKß
|
ADP-Glo
|
96/384 well
|
E224
|
IKKα
|
ADP-Glo
|
96/384 well
|
E225
|
InsR
|
ADP-Glo
|
96/384 well
|
E226
|
IRAK4
|
ADP-Glo
|
96/384 well
|
E227
|
ITK
|
ADP-Glo
|
96/384 well
|
E228
|
JAK3
|
ADP-Glo
|
96/384 well
|
E229
|
JNK1
|
ADP-Glo
|
96/384 well
|
E230
|
JNK3
|
ADP-Glo
|
96/384 well
|
E231
|
KDR
|
ADP-Glo
|
96/384 well
|
E232
|
KHS1
|
ADP-Glo
|
96/384 well
|
E233
|
LCK
|
ADP-Glo
|
96/384 well
|
E234
|
Lipid kinase
|
ADP-Glo
|
96/384 well
|
E235
|
LRRK2
|
ADP-Glo
|
96/384 well
|
E236
|
LYN B
|
ADP-Glo
|
96/384 well
|
E237
|
MAPKAPK2
|
ADP-Glo
|
96/384 well
|
E238
|
MAPKAPK3
|
ADP-Glo
|
96/384 well
|
E239
|
MAPKAPK5
|
ADP-Glo
|
96/384 well
|
E240
|
MARK1
|
ADP-Glo
|
96/384 well
|
E241
|
MELK
|
ADP-Glo
|
96/384 well
|
E242
|
MET
|
ADP-Glo
|
96/384 well
|
E243
|
MET(M1250T)
|
ADP-Glo
|
96/384 well
|
E244
|
MINK1
|
ADP-Glo
|
96/384 well
|
E245
|
MLCK
|
ADP-Glo
|
96/384 well
|
E246
|
MLK1
|
ADP-Glo
|
96/384 well
|
E247
|
MLK2
|
ADP-Glo
|
96/384 well
|
E248
|
MRCKa
|
ADP-Glo
|
96/384 well
|
E249
|
MSK1
|
ADP-Glo
|
96/384 well
|
E250
|
MSK2
|
ADP-Glo
|
96/384 well
|
E251
|
MST1
|
ADP-Glo
|
96/384 well
|
E252
|
MYO3β
|
ADP-Glo
|
96/384 well
|
E253
|
Name
|
ADP-Glo
|
96/384 well
|
E254
|
NEK2
|
ADP-Glo
|
96/384 well
|
E255
|
NEK3
|
ADP-Glo
|
96/384 well
|
E256
|
NIK
|
ADP-Glo
|
96/384 well
|
E257
|
NUAK2
|
ADP-Glo
|
96/384 well
|
E258
|
p38B
|
ADP-Glo
|
96/384 well
|
E259
|
p38α
|
ADP-Glo
|
96/384 well
|
E260
|
p38γ
|
ADP-Glo
|
96/384 well
|
E261
|
P38δ
|
ADP-Glo
|
96/384 well
|
E262
|
p70S6K
|
ADP-Glo
|
96/384 well
|
E263
|
p70S6Kb
|
ADP-Glo
|
96/384 well
|
E264
|
PAK1/CDC42
|
ADP-Glo
|
96/384 well
|
E265
|
PAK3
|
ADP-Glo
|
96/384 well
|
E266
|
PAK4
|
ADP-Glo
|
96/384 well
|
E267
|
PASK
|
ADP-Glo
|
96/384 well
|
E268
|
PDGFRa(D842V)
|
ADP-Glo
|
96/384 well
|
E269
|
PDGFRa(T674I)
|
ADP-Glo
|
96/384 well
|
E270
|
PDGFRα
|
ADP-Glo
|
96/384 well
|
E271
|
PDGFRβ
|
ADP-Glo
|
96/384 well
|
E272
|
PDK1
|
ADP-Glo
|
96/384 well
|
E273
|
PI3K Lipid kinases
|
ADP-Glo
|
96/384 well
|
E274
|
PI3K-Glo
|
ADP-Glo
|
96/384 well
|
E275
|
PIM1
|
ADP-Glo
|
96/384 well
|
E276
|
PIM2
|
ADP-Glo
|
96/384 well
|
E277
|
PKA
|
ADP-Glo
|
96/384 well
|
E278
|
PKC
|
ADP-Glo
|
96/384 well
|
E279
|
PKCß1
|
ADP-Glo
|
96/384 well
|
E280
|
PKCα
|
ADP-Glo
|
96/384 well
|
E281
|
PKCβII
|
ADP-Glo
|
96/384 well
|
E282
|
PKCγ
|
ADP-Glo
|
96/384 well
|
E283
|
PKCδ
|
ADP-Glo
|
96/384 well
|
E284
|
PKCε
|
ADP-Glo
|
96/384 well
|
E285
|
PKCζ
|
ADP-Glo
|
96/384 well
|
E286
|
PKCθ
|
ADP-Glo
|
96/384 well
|
E287
|
PKCι
|
ADP-Glo
|
96/384 well
|
E288
|
PKCμ
|
ADP-Glo
|
96/384 well
|
E289
|
PKD2
|
ADP-Glo
|
96/384 well
|
E290
|
PLK1
|
ADP-Glo
|
96/384 well
|
E291
|
PRKG1
|
ADP-Glo
|
96/384 well
|
E292
|
PYK2
|
ADP-Glo
|
96/384 well
|
E293
|
RET
|
ADP-Glo
|
96/384 well
|
E294
|
RET(V804L)
|
ADP-Glo
|
96/384 well
|
E295
|
RET(Y791F)
|
ADP-Glo
|
96/384 well
|
E296
|
RIPK2
|
ADP-Glo
|
96/384 well
|
E297
|
ROCK1
|
ADP-Glo
|
96/384 well
|
E298
|
ROCK2
|
ADP-Glo
|
96/384 well
|
E299
|
RON
|
ADP-Glo
|
96/384 well
|
E300
|
RSK1
|
ADP-Glo
|
96/384 well
|
E301
|
SGK1
|
ADP-Glo
|
96/384 well
|
E302
|
SIK
|
ADP-Glo
|
96/384 well
|
E303
|
SLK
|
ADP-Glo
|
96/384 well
|
E304
|
SRC
|
ADP-Glo
|
96/384 well
|
E305
|
STK33
|
ADP-Glo
|
96/384 well
|
E306
|
SYK
|
ADP-Glo
|
96/384 well
|
E307
|
TAK1-TAB1
|
ADP-Glo
|
96/384 well
|
E308
|
TAOK1
|
ADP-Glo
|
96/384 well
|
E309
|
TBK1
|
ADP-Glo
|
96/384 well
|
E310
|
TGFbR1
|
ADP-Glo
|
96/384 well
|
E311
|
TGFβR2
|
ADP-Glo
|
96/384 well
|
E312
|
TNIK
|
ADP-Glo
|
96/384 well
|
E313
|
TOPK
|
ADP-Glo
|
96/384 well
|
E314
|
TRKA
|
ADP-Glo
|
96/384 well
|
E315
|
TRKB
|
ADP-Glo
|
96/384 well
|
E316
|
ULK1
|
ADP-Glo
|
96/384 well
|
E317
|
VRK2
|
ADP-Glo
|
96/384 well
|
E318
|
WNK1
|
ADP-Glo
|
96/384 well
|
E319
|
ZAK
|
ADP-Glo
|
96/384 well
|
E320
|
ZAP70
|
ADP-Glo
|
96/384 well
|
关键词:激酶活性检测技术服务,提供服务,技术服务,生物技术服务,蛋白相关服务