N-己酰-NBD-乳糖神经酰胺

H1629-001

N-己酰-NBD-乳糖神经酰胺 N-Hexanoyl-NBD-lactosylceramide

semisynthetic

C₄₂H₆₉N₅O₁₆

900

1mg

solid

98+% TLC

N-Hexanoyl-NBD-beta-D-lactosylsphingosine; N-C6:0-NBD-beta-D-Lactosylsphingosine; N-C6:0-NBD-Lactosylceramide

chloroform/methanol, 2:1

-20°C

1. Y. Hayashi et al. “A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates” Analytical Biochemistry, Vol. 345(2) pp. 181-186, 2005
2. Glyn Dawson “Glycosphingolipid levels in an unusual neurovisceral storage disease characterized by lactosylceramide galactosyl hydrolase deficiency: lactosylceramidosis” Journal of Lipid Research, Vol. 13 pp. 207-219, 1972
3. NanLing Gong “Lactosylceramide recruits PKC
/ and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells” Proceedings of the National Academy of Sciences, Vol. 101:17 pp. 6490-6495, 2004