N-Dodecanoyl-NBD-lactosylceramide

H1630-001

N-Dodecanoyl-NBD-lactosylceramide

semisynthetic

C₄₈H₈₁N₅O₁₆

984

1mg

solid

98+% TLC

N-Dodecanoyl-NBD-beta-D-lactosylsphingosine; N-C12:0-NBD-beta-D-Lactosylsphingosine; N-C12:0-NBD-Lactosylceramide

chloroform/methanol, 2:1

-20°C

1. Y. Hayashi et al. “A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates” Analytical Biochemistry, Vol. 345(2) pp. 181-186, 2005
2. Ravinder Pannu et al. “A Novel Role of Lactosylceramide in the Regulation of Tumor Necrosis Factor
-mediated Proliferation of Rat Primary Astrocytes: IMPLICATIONS FOR ASTROGLIOSIS FOLLOWING NEUROTRAUMA” Journal of Biological Chemistry, Vol. 280 pp. 13742-13751, 2005
3. Glyn Dawson “Glycosphingolipid levels in an unusual neurovisceral storage disease characterized by lactosylceramide galactosyl hydrolase deficiency: lactosylceramidosis” Journal of Lipid Research, Vol. 13 pp. 207-219, 1972
4. NanLing Gong “Lactosylceramide recruits PKC
/ and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells” Proceedings of the National Academy of Sciences, Vol. 101:17 pp. 6490-6495, 2004