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抗球蛋白GL-4(多克隆抗体)

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  • 发布时间:2019-05-29产品供应时间:长期有效

所在地:中国上海

企业类型:企业单位

公司地址:上海市徐汇区漕溪路

联系人:文 (女士)
手机:17715331663
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Cat. Number
1960
Chemical Name
抗球蛋白GL-4(多克隆抗体)
Mol. Weight
n/a
Qty 1
50 µl
Appearance
liquid
Application Notes
serum, not purified ,ELISA, TLC immunoblotting
Synonym
Polyclonal antibody to GL-4, isotype IgG/IgM
Storage condition
-20°C
References
  • Application Notes:

    Anti-globosides are very useful in the identification of globosides and immunotargeting cells that express globosides. Globoside is the P-antigen of the P blood group. An inability to convert globotriaosylceramide to globotetrahexylceramide leads to the Pk blood group phenotype. In this phenotype anti-globoside antibodies are produced.3 There have been indications that the antibodies directed against the globoside antigen on suppressor T cells stimulate the suppressor T cells, and that anti-globoside antibodies in cancer sera may play a role in causing immunodeficiency in cancer patients.4

    References:
    1. H. Yoshino, et al.,Journal of Neurochem., Vol 61, pp. 658, 1993
    2. S. Kusunoki, et al., Neurology, Vol. 37, pp.1795, 1987
    3. A. Hellberg, J. Poole, and M. Olsson, The Journal of Biological Chemistry, Vol. 277, pp. 29455, 2002
    4. R. Noguchi, M.D., N. Shinomiya, M.D., K. Nagai, Ph.D. and J. Yata, M.D., Japanese Journal of Clinical Oncology, Vol. 13, pp.335-342, 1983
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