超敏ECL发光液（NATURE文献采用）17100

产品介绍

用于辣根过氧化物酶(HRP)标记的蛋白或核酸检测。 超300家实验室应用3年，从未想过更换！

主要特点

Pg级别  Enlight^TM-Plus含高灵敏的发光增强剂，检测级别可以达到pg级。

低背景   Enlight^TM-Plus采用精准的发光底物，有效降低发光试剂造成的非特异发光和背景发光。

时间长   Enlight^TM-Plus采用特异的发光配方，发光时间非常长，有效从容实验。

应用于本产品发表的部分文献

1.Nature Communications. 2016 Mar 31. Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways.（低氧微环境协同TGF-β信号以及Hippo信号在肿瘤发展中的作用）( IF:11.329 )

2. Nat Cell Biol. 2015 Jan. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase.（低氧通过E3泛素连接酶SIAH2调控Hippo信号通路 ）( IF:19.679 )

3. Helicobacter. 2016 Apr 6. The Upregulation of TRAF1 Induced by Helicobacter pylori Plays an Antiapoptotic Effect on the Infected Cells.（由幽门螺杆菌引起的TRAF1上调在感染细胞中具有抗凋亡作用）

4. Acta Pharmacol Sin. 2016 Jan 25. Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway （小鼠急性肝损伤研究）

5. J Pharmacol Sci. 2016 Feb. SUMOylation of pregnane X receptor suppresses rifampicin-induced CYP3A4 and P-gp expression and activity in LS174T cells.（孕烷X 受体的类泛素化在LS174T细胞中抑制CYP3A4和 P-gp的表达和活性）

6. J Proteome Res. 2016 May 6. Silencing PRDX3 Inhibits Growth and Promotes Invasion and Extracellular Matrix Degradation in Hepatocellular Carcinoma Cells.（线粒体过氧化物还原酶PRDX3的沉默可以抑制肝癌细胞的生长并能促进肝癌细胞的侵袭和细胞外基质的降解）

7.Sci Rep, 2016 Apr 6. Trim69 regulates zebrafish brain development by ap-1 pathway（Trim69 蛋白通过ap-1通路调节斑马鱼脑部发育）( IF:5.578 )

8. Acta Biochim Biophys Sin (Shanghai) 2016 Mar 2. Intermolecular disulfide bond in the dimerization of S-periaxin mediated by Cys88 and Cys139.（由Cys88 和 Cys139介导的S-periaxin 蛋白二聚体中分子间的二硫键）

9. Mol Med Rep. Mol Med Rep. 2016 April 11 DNase I aggravates islet β-cell apoptosis in type 2 diabetes （DNase I 加重2型糖尿病中胰岛β-cell的凋亡）

10.Journal of Nanomaterials. 2015 Jan. Investigations into the biocompatibility of nanohydroxyapatite coated magnetic nanoparticles under magnetic situation (纳米羟基磷灰石包覆的磁性纳米粒子的生物适应性）.

11.Biomed Eng Online. 2015 Apr 15. Porous deproteinized bovine bone scaffold with three-dimensional localized drug delivery system using chitosan microspheres.（采用壳聚糖微球的多孔牛骨支架三维局部药物输送系统）

12.J Biol Chem. 2015 Jul 24. Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.（Polo样激酶1（Plk1）通过影响人端粒酶逆转录酶（hTERT）稳定性从而上调端粒酶活性）.

13.J Zhejiang Univ Sci B.. 2015 Sep. Protective effect of L-carnitine in cyclophosphamide-induced germ cell apoptosis.（左旋肉碱对环磷酰胺致病菌引起的生殖细胞凋亡的保护作用）

14.Mol Med Rep.. 2015 Sep. Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis.（肌球蛋白轻链激酶抑制剂ML7对动脉硬化模型小鼠的血管内皮功能障碍的提高作用）

15.Drug metab Dispos. 2015 Mar. Therapeutic efficacy of Wuzhi tablet (Schisandra sphenanthera Extract) on acetaminophen-induced hepatotoxicity through a mechanism distinct from N-acetylcysteine.（华中五味子提取物对醋氨酚肝损伤的治疗效果）.

16.Cell Physiol Biochem. 2015 Jan 28. Effects of nicotinamide N-methyltransferase on PANC-1 cells proliferation, metastatic potential and survival under metabolic stress.（烟酰胺N-甲基转移酶对PANC-1细胞在代谢性应激条件下增殖、代谢转移潜能和生存力的作用研究）.

17.Drug metabolism and Disposition 2015 December 10. Hepato-Protective Effects of Schisandra Sphenanthera Extract against Lithocholic Acid-Induced Cholestasis in Mice are Associated With the Activation of PXR Pathway and Promotion of Liver Regeneration（华中五味子提取物对石胆酸诱导的胆汁淤积小鼠的肝保护作用）

18. Acta Pharmacol Sin. 2016 Jan 25. Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway （小鼠急性肝损伤研究）

19. Sci China Life Sci.. 2015 Sep. Kv1.3 channel blockade enhances the phagocytic function of RAW264.7 macrophages. ( Kv1.3通道的阻断可以增强RAW264.7巨噬细胞的吞噬作用）

20.Am J Physiol Heart Circ Physiol. 2015, Sep 2. MicroRNA-141 regulates the expression level of ICAM-1 on endothelium to decrease myocardial ischemia-reperfusion injury. (MicroRNA-141调节内皮细胞ICAM-1的表达水平以降低心肌缺血再灌注损伤）

21.BMC Complement Altern Med. 2015 May 27. Yi Qi Qing Re Gao formula ameliorates puromycin aminonucleoside-induced nephrosis by suppressing inflammation and apoptosis.（中药通过抑制炎症和细胞凋亡改善肾病）

22.J Virol. 2015 Mar. Hepatitis B virus regulates apoptosis and tumorigenesis through the microRNA-15a-Smad7-transforming growth factor beta pathway.（乙型肝炎病毒通过microrna-15a-smad7转化生长因子β通路调节细胞凋亡和肿瘤发生）

23.Cell Physiol Biochem. 2015 Sep. 11 Cryptotanshinone Reverses Cisplatin Resistance of Human Lung Carcinoma A549 Cells through Down-Regulating Nrf2 Pathway.( 隐丹参酮通过下调Nrf2通路逆转人肺腺癌A549细胞的顺铂耐药性）

24.FEBS Lett. 2011 Aug 4;585(15):2493-500.Cyclin T2: a novel miR-15a target gene involved in early spermatogenesis.

25.Mol Biol Cell. 2010 Dec;21(24):4312-24.A novel testis-specific GTPase serves as a link to proteasome biogenesis: functional characterization of RhoS/RSA-14-44 in spermatogenesis.

26.FEBS Lett. 2012 May 21;586(10):1497-503.Nemo-like kinase promotes etoposide-induced apoptosis of male germ cell-derived GC-1 cells in vitro.

27.J Cell Sci. 2012 Sep 15;125(Pt 18):4219-29.Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability.

28.PLoS One. 2012;7(6):e39165.Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice.

29.Ann Hepatol. 2013 Sep-Oct;12(5):815-21.Notch signal protects non-parenchymal cells from ischemia/reperfusion injury in vitro by repressing ROS.

30.PLoS One. 2013;8(3):e59610.Oxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperones.

31.J Proteome Res. 2013 Dec 13.Overexpression of CD38 Decreases Cellular NAD Levels and Alters the expression of Proteins Involved in Energy metabolism and Antioxidant Defense.

32.J Med Food. 2013 Apr;16(4):280-7.Effect of kai xin san on learning and memory in a rat model of paradoxical sleep deprivation.

33.metallomics. 2013 Jun 27;5(7):836-43.Vanadium compounds modulate PPARγ activity primarily by increasing PPARγ protein levels in mouse insulinoma NIT-1 cells.

34.PLoS One. 2013 Aug 15;8(8):e70884.Toxoplasma gondii protein disulfide isomerase (TgPDI) is a novel vaccine candidate against toxoplasmosis.

35.Pharmacology. 2013;92(3-4):121-30.Effect of phorbol 12-myristate 13-acetate on function and gene expression of P-glycoprotein in adriamycin-resistant K562/ADM cells.

36.Chem Biol Interact. 2014 Feb 14;213C:44-50.Down-regulation of P-gp expression and function after Mulberroside A treatment: Potential role of protein kinase C and NF-kappa B.

37.Diabetes Res Clin Pract.2014 Jan 30. The changes of neutrophil gelatinase-associated lipocalin in plasma and its expression in adipose tissue in pregnant women with gestational diabetes.

38.European Journal of Lipid Science and Technology.2014 Jan 17:255–265. Comparative study of DHA‐enriched phospholipids and EPA‐enriched phospholipids on metabolic disorders in diet‐induced‐obese C57BL/6J mice

运输与储存

常温运输，储存于4℃。

安全性

本品无特殊毒性。如不慎沾染，用清水冲洗即可。

质量保证

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