小片段RNA专用转染试剂R4000

产品介绍

Entranster^TM-R4000是英格恩生物（Engreen Biosystem）最新研发合成的针对siRNA、microRNA、mimic、inhibitor、mRNA和shRNA等RNA的转染试剂。Entranster^TM-R4000不仅可以转染小RNA，而且针对mRNA等长链RNA优化。由于纳米技术的应用，Entranster^TM-R4000能做到高达90%的转染效率和60-90%的沉默效率，对难转染细胞和原代细胞也非常适用。

应用范围

小RNA转染。包括siRNA转染，miRNA，mimic，inhibitor等。 长链的mRNA和shRNA转染，针对mRNA和长链的shRNA等RNA转染优化。 可转染动物细胞、昆虫细胞等，也可以转染原代细胞、悬浮细胞和原代细胞等传统难转染细胞。

主要特点

纳米聚合物，转染效果优于脂质体转染试剂 高效转染;

●沉默效率高，可以达到90％以上的沉默效率 低细胞毒性;

●有血清转染，无须反复更换培养基 原代细胞、悬浮细胞和敏感细胞都能转

应用于本产品的文献

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2.Journal of Experimental & Clinical Cancer Research. 2016 Sep 17. Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells.（p21基因激活与人类癌细胞中dsRNA的机制和功能）

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9.Apoptosis. 2015 Jan. RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells.（成纤维细胞瘤细胞研究）

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11.Mol Biosyst. 2015 Nov The involvement of aquaporin 1 in the hepatopulmonary syndrome rat serum-induced migration of pulmonary arterial smooth muscle cells via the p38-MAPK pathway.（肝肺综合征相关的研究）

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23.Journal of Radiation Research. 2012 June 6. MicroRNA-148b enhances the radiosensitivity of non-Hodgkin’s Lymphoma cells by promoting radiation-induced apoptosis.

24.J Cell Sci. 2012 May 28. Regulation of apoptosis by Bat3-enhanced YWK-II protein/APLP2 stability.

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26.Genes Immun. 2012 Oct 4.TGF-β-associated miR-27a inhibits dendritic cell-mediated differentiation of Th1 and Th17 cells by TAB3, p38 MAPK, MAP2K4 and MAP2K7.

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30.J Immunol. 2013 Jan 25.Multiple Tumor-Associated MicroRNAs Modulate the Survival and Longevity of Dendritic Cells by Targeting YWHAZ and Bcl2 Signaling Pathways.

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