进口鞘氨醇磷酸盐 D-erythro-Dihydrosphingosine-1-phosphate

H1852

进口鞘氨醇磷酸盐 D-erythro-Dihydrosphingosine-1-phosphate

19794-97-9

synthetic

C₁₈H₄₀NO₅P

382

5mg

solid

98+% TLC

chloroform/methanol/40% dimethylamine, 5:15:3, 1mg/ml; chloroform plus a few drops of TFA

-20°C

1. S. Bu et al. “Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts” The FASEB Journal, Vol. 20(1) pp. 184-186, 2006
2. S. Bu et al. “Opposite Effects of Dihydrosphingosine 1-Phosphate and Sphingosine 1-Phosphate on Transforming Growth Factor-_/Smad Signaling Are Mediated through the PTEN/PPM1A-dependent Pathway” Journal of Biological Chemistry, Vol. 283(28) pp. 19593-19602, 2008
3. E. Berdyshe “De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells” Cellular Signaling, Vol. 18(10) pp. 1779-1792, 2006